Tadalista Super Active, like other medications containing Tadalafil, works by increasing blood flow to the penis, which helps men with erectile dysfunction achieve and maintain an erection. However, sexual stimulation is still required for the medication to work effectively. Here's why: Mechanism of action: Tadalafil, the active ingredient in Tadalista Super Active, belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It works by inhibiting the enzyme phosphodiesterase type 5, which is involved in the regulation of blood flow in the penis. By blocking this enzyme, Tadalafil allows the blood vessels in the penis to relax and dilate, increasing blood flow and leading to an erection. Nitric oxide release: Sexual stimulation triggers the release of nitric oxide in the penis, which stimulates the production of cyclic guanosine monophosphate (cGMP), a chemical messenger that helps relax the smooth muscles of the penile arteries and increase blood flow to the penis. Tadalista Super Active enhances the effects of nitric oxide by preventing the breakdown of cGMP, allowing it to accumulate and prolong its effects. Enhanced response: While Tadalafil can help facilitate an erection by increasing blood flow to the penis, sexual stimulation is still necessary to initiate the process. Sexual arousal and stimulation trigger the release of nitric oxide, which is essential for the activation of the physiological pathways involved in achieving an erection. Without sexual stimulation, the release of nitric oxide and subsequent activation of these pathways may not occur, and Tadalista Super Active may not be as effective in producing an erection. In summary, while Tadalista Super Active can enhance the physiological mechanisms involved in achieving an erection, sexual stimulation is still necessary to initiate the process. Without sexual arousal and stimulation, the medication may not work as effectively. It's essential to communicate with a healthcare provider to understand how to use Tadalista Super Active properly and to address any questions or concerns about its effectiveness.