Taking Tadarise 10 treats erectile dysfunction and helps with impotence-related problems in men aged 18 to 65 years. When Tadalafil takes effect, it blocks the PDE5 enzyme and allows blood to flow to the enlarged organ. With water before engaging in sexual activities. The medicine takes about 30 minutes to start working. This medicine should not be used if the patient is below 18 years of age as this medicine is prescribed for adult males only.