What is the mechanism of action of   Malegra professional?

Malegra Professional is a medication used to treat erectile dysfunction (ED) in men. It contains Sildenafil Citrate as its active ingredient. The mechanism of action of Malegra Professional revolves around its ability to inhibit an enzyme called phosphodiesterase type 5 (PDE5).

Here’s how it works:

PDE5 Inhibition: Sildenafil Citrate in Malegra Professional selectively inhibits PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis. cGMP is a substance that promotes smooth muscle relaxation and vasodilation (widening of blood vessels).

Smooth Muscle Relaxation: When PDE5 is inhibited by Sildenafil Citrate, levels of cGMP increase in the penis. This leads to relaxation of smooth muscles in the blood vessels of the corpus cavernosum (erectile tissue of the penis).

Increased Blood Flow: As the smooth muscles relax and the blood vessels dilate, blood flow to the penis increases. This enhanced blood flow is crucial for achieving and maintaining an erection sufficient for sexual activity.

Erection Maintenance: Malegra Professional helps men with ED to achieve and sustain erections by facilitating the natural physiological process of penile erection in response to sexual stimulation.

It’s important to note that Malegra Professional, like other medications containing Sildenafil Citrate, does not cause erections on its own. Sexual arousal and stimulation are necessary for the medication to be effective. The onset of action typically occurs within 30 to 60 minutes after taking the medication orally, and the effects may last up to 4 to 6 hours.