Filitra 40 mg is a medication used to treat erectile dysfunction (ED) in men. It contains Vardenafil as its active ingredient, which belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Here’s how Filitra 40 mg works to treat ED:

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   Mechanism of Action: Vardenafil in Filitra 40 mg works by inhibiting the enzyme PDE5. Normally, PDE5 breaks down cyclic guanosine monophosphate (cGMP), a substance that relaxes smooth muscles in the blood vessels of the penis during sexual stimulation. By inhibiting PDE5, Vardenafil allows cGMP to accumulate and persist longer, which promotes increased blood flow into the penis. This improved blood flow helps men achieve and maintain an erection suitable for sexual activity.

   
   


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   Onset and Duration: Filitra 40 mg is typically taken orally with water, about 30 minutes to 1 hour before anticipated sexual activity. The effects of Vardenafil usually begin within 15-30 minutes of ingestion, with peak effectiveness occurring within about an hour. The duration of action is typically around 4 to 6 hours, during which time a man is more responsive to sexual stimulation.

   
   


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   Sexual Stimulation Requirement: It’s important to note that Filitra 40 mg, like other PDE5 inhibitors, requires sexual stimulation to be effective. Simply taking the medication without sexual arousal will not result in an erection.

   
   


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   Effectiveness: Clinical studies have shown Vardenafil to be effective in improving erectile function and enhancing sexual performance in a significant percentage of men with ED. It is considered a reliable treatment option for many individuals.

   
   


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   Safety Considerations: Filitra 40 mg should be used as prescribed by a healthcare provider. It’s important to follow dosage instructions carefully and not exceed the recommended amount. Common side effects may include headache, flushing, indigestion, nasal congestion, and dizziness. Serious side effects such as priapism (prolonged erection) are rare but require immediate medical attention.

   
   


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   Precautions: Filitra 40 mg should not be taken by individuals who are also using nitrates for chest pain or heart problems, as this combination can cause a sudden and serious decrease in blood pressure. It should also be used with caution in individuals with certain medical conditions such as heart disease, low blood pressure, or liver or kidney problems.