Individual tolerance and sensitivity to sildenafil, the active ingredient in Forzest 20 mg, play a significant role in determining the risk of adverse effects when taking a higher dose like 200 mg. Tolerance refers to the body's response to a medication over time, while sensitivity relates to how strongly an individual reacts to a given dose of the medication.

Role of Tolerance and Sensitivity:

1. 
   

   Tolerance: With repeated use of sildenafil, some individuals may develop tolerance, meaning they require higher doses to achieve the desired therapeutic effect. However, increasing the dose without medical supervision can lead to an increased risk of adverse effects.

   
   


2. 
   

   Sensitivity: Some individuals may be more sensitive to sildenafil, meaning they are more likely to experience side effects even at lower doses. For these individuals, taking a higher dose like 200 mg can significantly increase the risk of adverse effects.

   
   

Risks of Taking a 200 mg Dose:

1. 
   

   Increased Side Effects: Taking a higher dose of sildenafil, such as 200 mg, can increase the likelihood and severity of side effects. Common side effects may include headache, flushing, indigestion, and visual disturbances. More severe side effects like priapism (prolonged erection lasting more than 4 hours), sudden hearing loss, or cardiovascular events may also occur.

   
   


2. 
   

   Cardiovascular Risks: High doses of sildenafil can lower blood pressure, potentially leading to dizziness, fainting, or even more severe cardiovascular events, especially in individuals with pre-existing heart conditions or those taking medications that affect blood pressure.

   
   


3. 
   

   Drug Interactions: A higher dose increases the risk of drug interactions, especially with medications that affect liver function, blood pressure, or heart rhythm. Combining sildenafil with other drugs that have similar effects can amplify these risks.