Tadalista 20 mg, which contains Tadalafil, typically starts to work within 30 to 60 minutes after ingestion. However, it may take a little longer for some individuals, depending on factors such as metabolism and whether the medication is taken with food. Here’s how it works in the body: Onset of Action: Tadalista generally begins to show effects within 30 to 60 minutes. This is when it helps relax the blood vessels in the penis, allowing increased blood flow and facilitating an erection in response to sexual stimulation. Some men may experience effects slightly faster, while others may find that it takes a bit longer, especially if they have a slower metabolism or take the medication with a heavy meal. Duration of Effect: One of the key features of Tadalafil (the active ingredient in Tadalista) is its long duration of action, which can last up to 36 hours. This is why Tadalista 20mg is sometimes referred to as the "weekend pill." This long window of effectiveness gives men the flexibility to engage in sexual activity at any time within that period without needing to plan exactly when to take the medication. Food and Alcohol Interaction: Food: While Tadalista can be taken with or without food, a heavy or high-fat meal may delay its onset of action. It is generally absorbed more quickly on an empty stomach. Alcohol: Consuming alcohol in moderation does not significantly affect the onset of action of Tadalista, but excessive alcohol consumption can reduce its effectiveness and potentially cause side effects. Individual Factors: Metabolism: Individual factors, such as age, liver function, and other medications being taken, may influence how quickly Tadalista works. For example, men with liver issues may experience a delayed onset or stronger effects. Sexual Stimulation: Tadalista does not cause an erection without sexual arousal. It helps the body respond to sexual stimulation, so it is important to understand that the medication itself is not a stimulant but works in conjunction with physical or psychological arousal. Tadalista 20 mg typically begins to work within 30 to 60 minutes after ingestion, though it may vary slightly depending on individual factors. Its effects can last for up to 36 hours, providing flexibility in the timing of sexual activity.