Aurogra 100 mg contains the active ingredient Sildenafil, which is commonly used to treat erectile dysfunction. When considering interactions with antibiotics or antifungal medications, it's important to be aware that certain combinations can affect how medications are metabolized in the body. Specifically, antibiotics and antifungal medications can interfere with the activity of enzymes in the liver that are responsible for breaking down medications. Sildenafil is primarily metabolized by enzymes in the liver, mainly by an enzyme called CYP3A4. Some antibiotics and antifungal medications can inhibit or induce these enzymes, potentially affecting the metabolism of Aurogra 100 mg dosage and altering its effectiveness or increasing the risk of side effects. Macrolide Antibiotics (e.g., erythromycin, clarithromycin) Macrolide antibiotics can inhibit the activity of CYP3A4 enzymes, which may lead to higher levels of sildenafil in the bloodstream. This could increase the risk of side effects associated with sildenafil, such as headache, dizziness, and low blood pressure. It's important to note that individual reactions can vary, and not everyone who takes sildenafil in combination with these medications will experience interactions. However, it's recommended to exercise caution and consult a healthcare provider before combining Aurogra 100 mg (sildenafil) with any antibiotics or antifungal medications. If you're prescribed antibiotics or antifungal medications and you're also taking Aurogra 100 mg, it's advisable to inform your healthcare provider about all the medications you're currently using. They can provide personalized advice and monitor your health to ensure your safety and well-being.